Oncology

Understanding Chronic Lymphocytic Leukemia (CLL)

ID: 08035028

Understanding Chronic Lymphocytic Leukemia (CLL)

Understanding Chronic Lymphocytic Leukemia (CLL)
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Course Length:

  • 35 topics
  • 50 minutes of seat time

Language:

  • English

Course Features:

  • Audio narration
  • Animations
  • Progress checks
  • Pop quizzes
  • Final assessment

Target Audience:

  • Medical professionals
  • Medical students
  • Pharmaceutical representatives
  • Nurses

Description:

Leukemia is a type of cancer that originates in blood-producing organs, such as the bone marrow, and causes the uncontrolled proliferation of white blood cells. Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in adults in Western countries. This learning program is designed to introduce you to the main clinical features of CLL. The program begins with a brief overview of the classification of CLL, including a presentation of the hierarchy of lymphomas and the 2 forms of CLL. You will then learn about the tools used to establish diagnosis and determine prognosis for CLL. You will also learn about the clinical management of CLL.

Upon completion of this learning program, you will be able to:

  • Define CLL and identify its 2 disease subtypes.
  • Describe the general epidemiology trends and risk factors for CLL.
  • Explain the tools used to establish diagnosis and determine prognosis for CLL.
  • Discuss the clinical management of CLL.
  1. GETTING STARTED
    1. Sound Check
    2. Disclaimer
    3. Welcome
    4. Navigation Instructions
  2. STAYING FOCUSED
    1. Introduction
    2. Learning Objectives
  3. EPIDEMIOLOGY AND ETIOLOGY OF CLL
    1. Case Study and Overview
    2. Classification of CLL
    3. Cellular Origins of CLL
    4. CLL Disease Subtypes
    5. Molecular Genetics of CLL
    6. Epidemiology
      • Popup: Age, Gender, and Race
      • Popup: Family History and Genetic Predisposition
    7. Progress Check
  4. DIAGNOSIS AND PROGNOSIS OF CLL
    1. Case Study and Overview
    2. Clinical Presentation and Differential Diagnosis
    3. Peripheral Blood Tests
    4. Immunophenotyping and Flow Cytometry
    5. Fluorescence in situ Hybridization
    6. Bone Marrow Aspiration and Biopsy
    7. Staging
      • Popup: Rai System
      • Popup: Binet System
    8. Prognostic Markers
      • Popup: IgV Mutational Status
      • Popup: CD38 Immunophenotype
      • Popup: ZAP-70 Expression
      • Popup: Chromosomal Abnormalities
      • Popup: Other Prognostic Factors
    9. Clinical Complications
    10. Progress Check
  5. CLINICAL MANAGEMENT OF CLL
    1. Case Study and Overview
    2. Treatment Initiation
    3. Chemotherapy
      • Popup: Alkylating Agents
      • Popup: Purine Nucleoside Analogs
      • Popup: Bifunctional Agents
    4. Immunotherapy
    5. Combination Therapies
      • Popup: Fludarabine, Cyclophosphamide, and Rituximab
      • Popup: Fludarabine and Rituximab
      • Popup: Pentostatin, Cyclophosphamide, and Rituximab
      • Popup: Bendamustine and Rituximab
    6. Supportive Care
    7. Recurrent Disease
    8. Transformation
    9. Progress Check
  6. TEST YOUR ACQUIRED KNOWLEDGE
    1. Summary
    2. Final assessment
  7. END OF PROGRAM
  8. GLOSSARY
  9. REFERENCES



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